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This document specifies the safety requirements for the integration of machinery into a system. It gives requirements and recommendations for inherently safe design, safeguarding and complementary protective measures, and information for use of an integrated manufacturing system (IMS). This document is not intended to cover safety aspects of individual machines and equipment that can be covered by standards specific to those machines and equipment. Therefore, it deals only with those safety aspects for the safety-relevant interconnection of the machines and components. Where component machines of an integrated machinery system are operated separately or individually, the safety requirements of the relevant safety standards for these machines and equipment apply. This document is also applicable when a modification of an existing IMS results in a new configuration, function, capability or location. This document deals with the significant hazards, hazardous situations or hazardous events when used as intended and under specified conditions of misuse which are reasonably foreseeable. This document also provides requirements for IMS used in applications as following, but does not cover the hazards related to Emission of acoustic noise could be identified to be a significant hazard but the reduction of noise emissions is not covered in this document.